My body cannot process synthetic hormones but I was born with low amounts of certain hormones. If I do not supplement them, I am miserable, depressed and become very unstable. My family suffers, my ability to do anything does too. The imbalance in hormones also caused me to have a lifetime of serious reproductive issues (pros, endometriosis, bleeding disorder). I have been taking them fir about 10 years, 4 years prior to my complete hysterectomy (age 36) & for the past 6 years since the surgery. A hysterectomy at 36 REQUIRES HRT afterwards, but I can’t handle synthetic hormones & have proved it with several drs. I NEED THIS! Don’t take away the only medication that has ever worked!