Bioidentical hormones turned my life around. I had been suffering for a year with depression (and I never had depression until 51). Attempts at anti-depressants made it worse so I discontinued them. In about a week or two, after suffering for a year, the bioidentical hormones brought me back to myself. It was a miracle for me. I literally got my life back! I was so thankful to have found doctors who checked my hormone levels (and "vitamin" D levels too). I have had turnarounds in other aspects of my health. A year or so after beginning them, I stopped wearing glasses, no more aortic insufficiency after having it retested a few times, and got my libido back which had been totally gone. I believe there are positive impacts to health overall and may stop some of the negative effects of aging. If something is working so well, why interfere with it. I feel stronger and healthier now than in my 40's. I would be devastated!