As someone who had Epstein-Barr virus, I began taking bioidentical hormones when I was pre-menopausal to help me sleep to help me keep my immune system function and help me feel better. After many years on bioidenticals, and once I was through menopause, my Kaiser doctor recommended I stop taking them. I worked with my acupuncturist to phase off them. About five years later, I wasn't feeling well much of the time and had been diagnosed with osteoporosis. My naturopathic doctor suggested I go back on bioidenticals. In addition, the recommendation was to add testosterone pellets to support my bones. After a year of testosterone pellet implants, there was a 5% improvement in my bone density (compared to a 12% decrease the year before). I am also taking compounded progesterone to assist with sleep and overall wellness and estrogen pellets to assist with vaginal dryness. My quality of life has been very positively impacted by compounded hormone treatment!