As a female in her mid-40's with two kids, the severe pre-menstrual symptoms (mood swings, tender breasts, cramps, sometimes acne too) and heavy period (super ultra doesn't even cover) made every month challenging (if a meeting ran late, I would bleed through my jeans and had to go home). The combination of testosterone cream and progresterone pills have made every month's menstrual cycle "normal" and the symptoms leading to my period less severe/miserable and feels normal.