After trials of various HRT combinations, utilization of an estradiol patch in combination, with 150 milligrams of compounded Progesterone, has provided me with the alleviation of menopausal symptoms. I experience a full night's sleep, clearer thinking during the day, and no hot flashes, etc. I would not want to think of returning to the days prior to the initiation of this combination of compounded medications and the benefits provided by them.