After a total hysterectomy I was put on an estradiol patch, but found that I was still having some unpleasant symptoms. My OBGYN doctor recommended a testosterone/progesterone cream compounded by a local compounding chemist. We have tweaked the dosage over the years, but I have been thrilled with the results. Insurance has never paid for it, and it is a financial strain on our budget, but we have paid out of pocket for it for over 20 years because of its effectiveness. Please do not let the FDA take this away from me!