16 years ago I was very messed up, crying for no reason, depressed, couldn't think right, tired, and hot flashes. EVERY menopausal systems there is, I had. I realized it was menopause and I started researching what I could do. After trying other things I learned everything there is about bioidentical hormones and having been using them DAILY for 16 years. They are safer then what the FDA has approved for use such Premarin. I have never felt better in my life. Please do not take them away. They're compounded for each person of natural ingredients. They are amazing.